The new classification of antihypertensive drugs is divided into 11 categories. In the 11th category of "other" categories, the list of drugs is two -two.Some readers are surprised, isnt the two-two double-dual-dual-dual-dual-dual-dual-dual-dual-dual-dual-duplex#0-- 0->?How can you still lower blood pressure?
Two-metammer can lower blood pressure, really!
Some scholars have done a lower -blood voltage research on comparison of two -metammer and antihypertensive drugs. The comparison of antihypertensive drugs are Fushezeli and chose patients with high insulinmia.It was found that in the crowd of crowd with high insulin ledmia, the two-meta duality has a similar antihypertensive effect with Finsinbley, and it also has a good synergistic effect when combined with the joint application.
The combination of dual-metammer and antihypertensive drugs can also enhance the antihypertensive effect.There are studies of ammonia horizon or levodine horizon combined with di metama dual -hypertrophic hypertension, Patartan combined with dual -hypertension combined metabolic syndrome.Three or more patients with antihypertensive drugs have poor effects, whether or not, the blood pressure of the two meta and duality has a significant decline in blood pressure.
Hypertension and diabetes have commonly used factor and common risk factors. Often, you have me and you have you.
Patients with hypertension should screen diabetes. Patients with diabetes often measure blood pressure, because these two diseases are often accompanied by each other.Because patients with hypertension and diabetes often have unhealthy lifestyles, overweight or obesity, sugar metabolism disorders, diabetes, abnormal blood lipids, and high hyperuric acid.The common pathogenic mechanism is insulin resistance, hyperin ledmia.
Most of the diabetes that our adults have type 2 are type 2 diabetes.The cause of the disease is not insulin deficiency, but insulin resistance.What do you mean?It is a type 2 diabetes. Because the cells in their own body are not sensitive to insulin, insulin cannot work, and the blood glucose cannot be metabolized normally, resulting in excessive insulin secretion in the body and high insulin ledmia.Patients with obesity, patients with metabolic syndrome, have high insulinmia.
Hypertrophymia causes diabetes and hypertension to coexist.
There are more insulin, and it is not necessary to play a bad effect.
In addition to affecting blood sugar and blood lipid metabolism, it can also cause hypertension.
High insulin ledmia can cause physical inflammation and damage blood vessel endothelial, and vascular endothelials secrete the factor that regulates blood vessels.In this way, insulin resistance has occurred, the endothelial function is also disordered, the resistance of blood vessels will increase, and the blood pressure will rise. High insulinmia will also activate the renal-vascular tension system that is closely related to hypertension. You can thinkSteem. High insulinmia can also excite the sympathetic nervous system in the body, and also increase blood pressure and accelerate heart rate. High insulin ledmia can also act on the kidneys, so that the sodium salt that the kidneys originally needed to be discharged and increased.The number of sodium (salt) in the body increases, the amount of water increases, and the blood volume increases.There are so many blood vessels, the blood volume increases, and the blood pressure is high.
High insulin ledmia causes diabetes and hypertension.Studies have found that more than 70%of people with diabetes are combined with hypertension and/or abnormal blood lipids.About 1/4 of the patients with hypertension are used with diabetes. If the blood glucose is damaged, the sugar tolerance is abnormal, or the two coexist, there will be about 70%of the blood sugar abnormal.
Two-metammer can reduce blood pressure because it can improve insulin resistance!
The drug of the two metformin can improve the sensitivity of cells to insulin and increase sensitivity.In this way, the cells have more blood sugar intake and utilization, and the heterogeneity and output of the liver glycogen have also decreased, and the blood sugar drops.Blood glucose drops, insulin does not use excessive secretion, and high insulin ledmia will improve.The two -metammer itself does not stimulate the secretion of insulin and does not cause high insulinmia, because it is not directly lowering blood sugar, and generally does not cause hypoglycemia. Safety is better.
In the action of the two-meta dual-dual-dual-dual-dual-dual-duality, it can also promote the secretion of high cash-to-1 peptide-1 in the body.This substance is also made into hypoglycemic drugs, such as clinically used Lichel peptides, Smeglugin, and so on.This type of drug is the 11th type of antihypertensive drug ().
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